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KMID : 0363320110320030444
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Journal of Korean Oriental Internal Medicine
2011 Volume.32 No. 3 p.444 ~ p.450
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One Case of Drug-Induced Liver Injury after Taking Gamiyukgunja-tang
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Shin Woo-jae
Kim Tae-yeon
Park Yu-jin
Moon Ju-Ho
Ko Heung
Kim Gi-Tae
Shin Seon-Mi
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Abstract
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Recently, acute toxic liver injury has been reported to be the most common cause of acute hepatitis. We witnessed one case of hepatic injury which suggested drug-induced hepatitis by herbal medication (Gamiyukgunja-tang). This patient, diagnosed cerebral infarction, was treated with herbal medication and physical therapy for improvement of right hemiparesis. In the course of treatment, this patient showed elevation of serum transaminase (ALT 129 IU/L, AST 150 IU/L), alkaline phosphatase (ALP 261 IU/L), and total bilirubin (2.0 IU/L), so we supposed toxic hepatitis by herbal medication. Saenggangeonbi-tang was administered for 8 days, ALT, AST, ALP, total bilirubin decreased within normal limits.
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KEYWORD
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drug-induced liver injury, Gamiyukgunja-tang (Jiaweiliujunzi-tang), Saenggangeonbi-tang
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